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Zyban– First Pill To Treat Nicotine Addiction

Smoking habit is one of the oldest mysteries as well as the nonsense of the Human Civilization. Everybody knows that nicotine harms badly the human health and nobody knows even more or less serious positive effect of it on people. Nevertheless the army of smokers grows with the speed of pandemia, involving thousands of new-comers everyday. What are they looking for in smoking is hardly to explain. But the main problem with smoking is that one can easily start smoking, but cannot give it up with the same ease. Statistics says that every year 34% of all smokers try to give up smoking, but only 2.5% succeed… Thanks God people invented medicine, which helps us to fight with health problems, and, while smoking on the level of nicotine addiction is one of the biggest health problems, - medicine offers several options to treat it.

First is nicotine replacement therapy. The main idea of it is to supply human organism with nicotine without the cigarette smoking, gradually decreasing the dose. Such treatment is available in forms of chewing gum, inhaler, patch or even the nasal spray. Pessimistic question arises here: “How the nicotine addiction can be treated with nicotine itself?” Optimistic answer for it is “It’s magic, but it’s true, gum can really help to quit smoking”. Finally the realistic explanation goes: nicotine patches are the entry level treatment of nicotine addiction, they are free to buy anywhere and can be experienced by any smoker on his own behalf. But in cases the gum does not help, special prescription drug exists - the second option in treating the nicotine addiction.

The first pill in this class and the most effective one for the time being is ZYBAN, marketed by Glaxo Wellcome Company and approved by the American Food and Drug Administration in year 1998. The main difference and obviously the biggest advantage of ZYBAN in comparison to patches, described above, is that ZYBAN does not contain nicotine. It helps to quit smoking, working on the neurological level and reducing the craving for nicotine in any form. The main working agent in ZYBAN is Bupropion, which was initially used as the anti-depressant. Probably this is just where the golden key lays. Indeed most people can not give up smoking because of terrible withdrawal symptoms, like irritability, frustration, anger, anxiety, depressed mood etc. ZYBAN, being the anti-depressant by its origin, significantly reduces such symptoms as well as crawling for cigarettes or urge to smoke.

The effectiveness of ZYBAN has been proved by many clinic tests. One of them involved about 1.500 chronic smokers and showed that within 4 weeks ZYBAN helped 49% of participants to quit smoking, while the nicotine patch helped only 36% of smokers.